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Contact Information

Ben & Catherine Ivy Foundation
6710 North Scottsdale Road
Suite 235
Scottsdale, AZ 85253
Phone: 480.659.9621
Fax: 480.659.9651

Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity
Monday, March 6th, 2017

Cancers evolve in rapidly changing environments from single cells into genetically heterogeneous masses. Darwinian evolution selects for survival of the fittest cells, that is, those that are best suited to their environment. Heterogeneity provides a pool of mutations upon which selection can act 1, 5–9. Cells that acquire fitness-enhancing mutations are more likely to pass

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Reporter gene imaging of targeted T cell immunotherapy in recurrent glioma
Tuesday, February 21st, 2017

High-grade gliomas are aggressive cancers that often become rapidly fatal. Immunotherapy using CD8+ cytotoxic T lymphocytes (CTLs), engineered to express both herpes simplex virus type 1 thymidine kinase (HSV1-TK) and interleukin-13 (IL-13) zetakine chimeric antigen receptor (CAR), is a treatment strategy with considerable potential. To optimize this and related immunotherapies, it would be helpful to

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St. Vincent de Paul: Culturally-grounded Diabetes Prevention Program
Thursday, February 9th, 2017

Obesity and type 2 diabetes (T2D) represent some of the most significant public health challenges facing our society. Disparities in obesity and T2D emerge early in life and disproportionately impact Latino populations. Latino youth exhibit higher rates of insulin resistance [1] and pre-diabetes [2] than white youth and nearly 30% of obese Latino youth exhibit

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T-Gen/Mayo
Thursday, January 19th, 2017

The survival of patients diagnosed with glioblastoma (GBM), the most deadly form of brain cancer, is compromised by the proclivity for local invasion into the surrounding normal brain, which prevents complete surgical resection and contributes to therapeutic resistance. Tumor necrosis factor-like weak inducer of apoptosis (TWEAK), a member of the tumor necrosis factor (TNF) superfamily,

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Nicholas Butowski, M.D., Selected to Direct Brain Tumor Research at UCSF
Thursday, December 10th, 2015

Research is funded by Ivy Foundation Scottsdale, Ariz. (Dec. 9, 2015) – Nicholas Butowski, M.D., has been selected to serve as the principal investigator of the Ivy Foundation Early Phase Clinical Trials Consortium from the University of California, San Francisco, Department of Neurological Surgery. Previously, the position was held by Michael Prados, M.D., who retired

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TGen identifies drug that could limit the spread of deadly brain tumors
Friday, November 20th, 2015

Study funded by Ivy Foundation shows PPF could help treat glioblastomas by sensitizing tumors to chemotherapy and radiation treatments PHOENIX, Ariz. — Nov. 12, 2015 — In a significant breakthrough, the Translational Genomics Research Institute (TGen) has identified a drug, propentofylline or PPF, that could help treat patients with deadly brain cancer. In a study

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The Ben and Catherine Ivy Foundation Funds Extension of Mayo Clinic Brain Cancer Study with $1.3 Million
Tuesday, June 9th, 2015

The Ben & Catherine Ivy Foundation (Ivy Foundation) announced an extension and funding of an additional $1.3 million for Mayo Clinic to study brain tumor vaccines that combine a patient’s immune stimulators with tumor cultures from other patients. The extension will include a second trial with patients whose brain cancer has returned.

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Ivy GAP
Thursday, May 14th, 2015

Robust new data added to the Ivy Glioblastoma Atlas Project (Ivy GAP) changes the scope and impact of this publicly available resource for researchers and clinicians searching for treatments for this most deadly and aggressive of brain cancers, glioblastoma multiforme.

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Brain Tumor Patients Put on Fast Track in Revolutionary Clinical Trial
Tuesday, March 10th, 2015

Barrow, Ivy, TGen, Karmanos ‘Phase 0’ Studies Evaluate if Drugs Can Reach Cancer in the Brain   PHOENIX, AZ — March 10, 2015 — Brain tumor experts at Barrow Neurological Institute at Dignity Health St. Joseph’s Hospital and Medical Center have launched a revolutionary fast-track approach to cancer research, giving new hope to brain cancer patients.

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Ben and Catherine Ivy Foundation Funds Barrow Neurological Brain Cancer Research Project
Wednesday, November 26th, 2014

Ben and Catherine Ivy Foundation Funds Barrow Neurological Brain Cancer Research Project

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Mayo Clinic Appoints Catherine Ivy to Arizona Leadership Council
Wednesday, October 1st, 2014

Mayo Clinic Appoints Catherine Ivy to Arizona Leadership Council

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TGen Receives Approval for Patient Enrollment in Brain Cancer Clinical Trial
Tuesday, September 2nd, 2014

Glioblastoma (GBM) Pilot Trial funded by Ivy Foundation SCOTTSDALE, Ariz. — September 2, 2014 — In 2012, The Ben & Catherine Ivy Foundation awarded $10 million in grants for two groundbreaking brain cancer research projects at the Translational Genomics Research Institute (TGen). One of those projects has officially received the final regulatory approval from University

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Swedish Neuroscience Institute Report
Monday, August 11th, 2014

The Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment Great strides have been made in the treatment of breast, colon and other common cancers in recent years. Yet, the life expectancy of a person diagnosed with glioblastoma, the most common form of malignant primary brain cancer, is only about 15 months — a

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Ivy Foundation expands Neurological Sciences Internship Program at TGen
Thursday, May 15th, 2014

Intensive training focuses on brain tumor research and neuroscience SCOTTSDALE, Ariz. — May 14, 2014 – The Arizona-based Ben & Catherine Ivy Foundation is expanding its Ivy Neurological Science Internship Program at the Translational Genomics Research Institute (TGen), enhancing one of the premier neuro-related biomedical internships in the state. Now in its third year, the Ivy

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Catherine Ivy Receives TGen’s John S. McCain Leadership Award
Friday, April 25th, 2014

Catherine Ivy, Founder and President of The Ben & Catherine Ivy Foundation, received TGen’s John S. McCain Leadership Award, named for U.S. Sen. John McCain of Arizona and annually presented for leadership and dedication that have made a significant impact in the fight against disease and helping patients worldwide. Ivy established her foundation in memory

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The Ben and Catherine Ivy Foundation Funds Society of St. Vincent de Paul Diabetes Program
Monday, July 22nd, 2013

Scottsdale, Ariz. (July 22, 2013) – The Ben & Catherine Ivy Foundation (Ivy Foundation) announced its funding of the Family Wellness Program managed by the Society of St. Vincent de Paul, Phoenix. The Ivy Foundation is the largest privately funded brain cancer research foundation in North America; Catherine Ivy is the founder and president of the Ivy Foundation. The

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Ivy Foundation Renews Support For TGen Program
Thursday, May 9th, 2013

The Arizona-based Ben & Catherine Ivy Foundation will fund a second year of the Ivy Neurological Science Internship Program at the Translational Genomics Research Institute (TGen). The internship program offers hands-on biomedical research experience for high school, undergraduate and aspiring medical school students pursuing careers in brain tumor research, neuroscience and neurogenomics. Through the program,

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Swedish Receives Ivy Foundation Grant
Friday, November 30th, 2012

Swedish Receives $2.5 Million Grant from the Ivy Foundation to Advance Brain Cancer Research The Ivy Center for Advanced Brain Tumor Treatment at Swedish discovers that an FDA-approved treatment for alcoholism may also work for brain cancer New funds from the Ivy Foundation will further this research SEATTLE — Nov. 29, 2012 — Swedish Medical

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Ivy Foundation Awards $10 Million to Stanford Professor to Advance the Fight Against Brain Tumors
Tuesday, October 4th, 2011

October 4, 2011 In 2011, the National Cancer Institute estimates that 22,340 persons in the United States will be diagnosed with brain and other nervous system cancers and that 13,110 individuals will die of these tumors. The most common and aggressive type of brain cancer in humans is glioblastoma multiforme (GBM), the disease that killed

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Swedish’s IVY Brain Tumor Center Launches Two New Clinical Trials to Treat Brain Cancer
Wednesday, September 21st, 2011

September 21, 2011 New treatment approaches use the DCVax tumor vaccine and C-14 labeled Temozolomide to improve outcomes in brain cancer SEATTLE, Wash. – September 21, 2011 – The Swedish Neuroscience Institute today announced that the Ivy Brain Tumor Center has launched two separate clinical trials for treating brain cancer. The first trial (IND No.

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Ivy Foundation taps Dana-Farber to Lead Innovative Brain Cancer Research
Monday, June 7th, 2010

“My colleagues and I are honored to share in the Ivy Foundation’s mission, and we’re very excited about the advances in treatment options that may come out of this project.” — Ronald DePinho, MD After enjoying long and distinguished careers in investment and financial planning, Ben and Catherine Ivy hoped to leverage their success and

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Award Targets Brain Tumor Research
Friday, October 9th, 2009

$691,930 awarded for In Silico Center of Excellence PHOENIX, Ariz. – Oct. 9, 2009 – SAIC-Frederick Inc., under its prime contract with the National Cancer Institute, has named the Translational Genomics Research Institute (TGen) as one of five national centers selected to conduct cancer experiments using advanced computer simulations. The award of the “In Silico

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Ivy Foundation Partners with BTFC: New RFA Announced
Thursday, April 16th, 2009

Contact Information: Ben and Catherine Ivy Foundation – Rob Tufel 650.324.3000 Brain Tumor Funders’ Collaborative Aims to Spur Development of Non-InvasiveResponse Markers for Human Gliomas Today, the eight North American private funding organizations comprising the Brain Tumor Funders’ Collaborative announced a new funding initiative aimed at accelerating development of non- or minimally- invasive methods for

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Ivy Foundation Project Kick-off Meeting Focuses on Collaboration
Friday, January 23rd, 2009

The Ivy Foundation held its first-ever research project kick-off meeting on January 23, 2009. The purpose of the meeting was to gather the 2008 Ivy Foundation awardees to move research forward by encouraging collaboration, fostering dialogue and providing an opportunity for an open exchange of ideas. Catherine Ivy, the Ivy Foundation founder, launched the event

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Ivy Foundation Target 2008: $12M in Brain Tumor Research Funding
Monday, July 7th, 2008

In 2008, The Ben and Catherine Ivy Foundation plans to award $12 million in research funding in support of multi-year research projects that address clinically relevant questions in diverse research areas. “The Ben and Catherine Ivy Foundation has heard from researchers across the country about the difficulty in obtaining funding for brain tumor research” said

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