USING PRE-CLINICAL EXPERIMENTAL MODELS, GLIOBLASTOMAS TUMORS DISPLAY THERAPEUTIC VULNERABILITY TO PHARMACOLOGIC TREATMENT WITH THE YAP/TAZ INHIBITOR AND PORPHYRIN DERIVATIVE VERTEPORFIN. TESTING OF AN FDA-APPROVED LIPOSOMAL FORMULATION OF VERTEPORFIN IN A PHASE 1/2 CLINICAL TRIALS IN HUMAN GLIOBLASTOMA PATIENTS AND TO IDENTIFY BIOMARKERS PREDICTIVE OF THERAPEUTIC RESPONSE TO THIS DRUG.

PI: Renee D. Read, Ph.D.
Assistant Professor of Pharmacology and Chemical Biology, Hematology and Medical Oncology
Emory University School of Medicine

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