Research Funded To Date

The Ben and Catherine Ivy Foundation is dedicated to finding a cure for brain cancer. We strive in improve the quality of life and increase the life expectancy of those diagnosed with brain cancer by funding promising research that creates more diagnostics and treatments for patients.

Since 2008, we have funded 36 separate institutions with over 114 different research grants totaling over $165 million. These grants have involved research in phase 0 clinical trials, biomarkers, genomics, imaging, immunotherapy, stem cell, vaccines, and the development of possible new drugs.

2008

DEVELOPMENT AND IMPLEMENTATION OF NOVEL MOLECULAR DIAGNOSTIC TOOLS TO GUIDE COMBINATION THERAPY FOR MALIGNANT GLIOMA PATIENTS

PIs: Paul S. Mischel, M.D.
Associate Director of Clinical Sciences
Institute for Molecular Medicine
University of California Los Angeles (UCLA)

Timothy F. Cloughesy, M.D.
Clinical Professor, Department of Neurology
Director, Neuro-Oncology Program
Co-Director, Henry E. Singleton Brain Cancer Research Program
University of California Los Angeles (UCLA)

Award: $1,500,000 over three years

p75ntr IS A RATIONAL DRUG TARGET FOR MALIGNANT GLIOMA

PI: Peter A. Forsyth, M.D.
Dept. Chair, Neuro-Oncology
University of Calgary

Award: $1,277,005 over three years

TARGETING GLIOBLASTOMA THROUGH TUMOR ENDOTHELIAL MARKER-1 (TEM-1)

PI: George Coukos, M.D., Ph.D.
Associate Professor
University of Pennsylvania

Award: $622,501 over two years

IVY GENOMICS-BASED MEDICINE (G.B.M.) PROJECT –STAGE I

PI and Consortium Leader: Michael Berens, Ph.D.
Deputy Director, Research Resources
Translational Genomics Research Institute (TGen)

Consortium member PIs:

Antonio Chiocca, M.D., Ph.D. and Sean Lawler, Ph.D., Ohio State University
Howard Colman, M.D., Ph.D., M.D. Anderson Cancer Center
G.Yancey Gillespie, Ph.D., University of Alabama at Birmingham
C. David James, Ph.D., University of California, San Francisco
Tom Mikkelsen, M.D., Henry Ford Hospital
Jann Sarkaria, M.D., Mayo Clinic, Rochester
Andrew Sloan, M.D., Case Western Reserve University School of Medicine
Craig Webb, Ph.D., Van Andel Research Institute

Consortium Collaboration Software: 5AM Solutions

Award: $3,240,343 over two years

GLIOMA CANCER STEM CELLS AND TUMOR-DERIVED MESENCHYMAL STEM CELLS: ROLE AND CROSSTALK IN HUMAN GLIOMAS

PIs: Kenneth Aldape, M.D.
Professor, Department of Pathology
MD Anderson Cancer Center

Frederick F. Lang, M.D.
Professor and Director of Clinical Research, Department of Neurosurgery
MD Anderson Cancer Center

Award: $1,500,000 over three years