Research Funded To Date

Since inception $91 million invested in a cure for brain cancer

2008

DEVELOPMENT AND IMPLEMENTATION OF NOVEL MOLECULAR DIAGNOSTIC TOOLS TO GUIDE COMBINATION THERAPY FOR MALIGNANT GLIOMA PATIENTS

PIs: Paul S. Mischel, M.D.
Associate Director of Clinical Sciences
Institute for Molecular Medicine
University of California Los Angeles  (UCLA)

Timothy F. Cloughesy, M.D.
Clinical Professor, Department of Neurology
Director, Neuro-Oncology Program
Co-Director, Henry E. Singleton Brain Cancer Research Program
University of California Los Angeles  (UCLA)

Award: $1,500,000 over three years

p75ntr IS A RATIONAL DRUG TARGET FOR MALIGNANT GLIOMA

PI: Peter A. Forsyth, M.D.
Dept. Chair, Neuro-Oncology
University of Calgary

Award: $1,277,005 over three years

TARGETING GLIOBLASTOMA THROUGH TUMOR ENDOTHELIAL MARKER-1 (TEM-1)

PI: George Coukos, M.D., Ph.D.
Associate Professor
University of Pennsylvania

Award: $622,501 over two years

IVY GENOMICS-BASED MEDICINE (G.B.M.) PROJECT –STAGE I

PI and Consortium Leader: Michael Berens, Ph.D.
Deputy Director, Research Resources
Translational Genomics Research Institute (TGen)

Consortium member PIs:

  • Antonio Chiocca, M.D., Ph.D. and Sean Lawler, Ph.D., Ohio State University
  • Howard Colman, M.D., Ph.D., M.D. Anderson Cancer Center
  • G.Yancey Gillespie, Ph.D., University of Alabama at Birmingham
  • C. David James, Ph.D., University of California, San Francisco
  • Tom Mikkelsen, M.D., Henry Ford Hospital
  • Jann Sarkaria, M.D., Mayo Clinic, Rochester
  • Andrew Sloan, M.D., Case Western Reserve University School of Medicine
  • Craig Webb, Ph.D., Van Andel Research Institute

Consortium Collaboration Software: 5AM Solutions

Award: $3,240,343 over two years

GLIOMA CANCER STEM CELLS AND TUMOR-DERIVED MESENCHYMAL STEM CELLS: ROLE AND CROSSTALK IN HUMAN GLIOMAS

PIs: Kenneth Aldape, M.D.
Professor, Department of Pathology
MD Anderson Cancer Center

Frederick F. Lang, M.D.
Professor and Director of Clinical Research, Department of Neurosurgery
MD Anderson Cancer Center

Award: $1,500,000 over three years
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