Research Funded To Date

The Ben and Catherine Ivy Foundation is dedicated to finding a cure for brain cancer. We strive in improve the quality of life and increase the life expectancy of those diagnosed with brain cancer by funding promising research that creates more diagnostics and treatments for patients.

Since 2008, we have funded 19 separate institutions with over 65 different research grants totaling almost $100 million. These grants have involved research in biomarkers, genomics, imaging, immunotherapy, stem cell, vaccines, and the development of possible new drugs.

2018

PHASE II, OPEN-LABEL STUDY TO ESTIMATE THE OVERALL RESPONSE RATES OF OLAPARIB IN SUBJECTS WITH RECURRENT/PROGRESSIVE IDH1/2-MUTANT SOLID TUMORS IN 3 COHORTS (GLIOMA, CHOLANGIOCARCINOMA, AND OTHER SOLID MALIGNANT TUMORS).

PI: Patricia LoRusso, DO
Professor of Medicine; Associate Director of Experimental Therapeutics
Yale Cancer Center

Award: $55,000

DEVELOPMENT OF A PROJECT TO CREATE AND DEPLOY AN ULTRA-RAPID CLINICAL TEST TO COMPREHENSIVELY PROFILE THE GENOMES OF PATIENTS WITH RECURRENT GLIOBLASTOMA.

PI: Timothy K. McDaniel, Ph.D.
Sr. Vice President of Emerging Opportunities
Translational Genomics Research Institute (TGen)

Award: $34,406

DEVELOPMENT OF A PROJECT TO ASSESS SINGLE CELL RNA SEQUENCING AS A QUALITY CONTROL METRIC IN THE INDUSTRIAL MANUFACTURE OF CHIMERIC ANTIGEN RECEPTOR T (CAR T) CELLS.

PI: Nicholas Banovich, Ph.D.
Assistant Professor in the Integrated Cancer Genomics Division
Translational Genomics Research Institute (TGen)

Award: $65,594

NEUROLOGICAL SCIENCES INTERNSHIP PROGRAM AT TGEN DESIGNED TO GIVE HIGH SCHOOL AND UNDERGRADUATE STUDENTS INTENSIVE, HANDS-ON RESEARCH EXPERIENCE WORKING ALONGSIDE A MENTOR-SCIENTIST TO LEARN ABOUT TRANSLATIONAL RESEARCH WHILE INVESTIGATING QUESTIONS WITHIN THE NEUROLOGICAL SCIENCES.

PI: Julie Euber
Manager of Education and Outreach
Translational Genomics Research Institute (TGen)

 

Award: $87,424

ESTABLISH A PHOENIX-BASED CENTER FOR GLIOBLASTOMA DRUG DISCOVERY – THE IVY BRAIN TUMOR RESEARCH CENTER-EMPHASIZING INDUSTRY-PARTNERED DRUG DEVELOPMENT PAIRED WITH A LARGE PORTFOLIO OF PHASE 0/II TRIALS AND RANDOMIZED PHASE II TRIALS.

PI: Nader Sanai, M.D., FAANS, FACS
Director, Division of Neurosurgical Oncology
Director, Barrow Brain Tumor Research Center
Barrow Neurological Institute

 

Award: $25,000,000 over ten years
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