Research Funded To Date

The Ben and Catherine Ivy Foundation is dedicated to finding a cure for brain cancer. We strive in improve the quality of life and increase the life expectancy of those diagnosed with brain cancer by funding promising research that creates more diagnostics and treatments for patients.

Since 2008, we have funded 19 separate institutions with over 65 different research grants totaling over $120 million. These grants have involved research in biomarkers, genomics, imaging, immunotherapy, stem cell, vaccines, and the development of possible new drugs.

SPECIFIC AND OPTIMAL THERAPY FOR GBM LEVERAGED FROM THE IVY GBM PROJECT TO IMPACT THE DESIGN OF CLINICAL TRIALS FOR GBM PATIENTS.

PI and Consortium Leader: Michael Berens, Ph.D.
Deputy Director, Research Resources
Translational Genomics Research Institute (TGen)

Award: $250,000

HIGH-THROUGHPUT CHEMICAL SCREEN OF PATIENT DERIVED GBM TUMOR INITIALIZING CELLS

PI: Greg D. Foltz, M.D.
Director, The Ben & Catherine Ivy Center for Advanced Brain Tumor Treatment
Swedish Medical Center

Award: $250,000

PERSONALIZED IMMUNOTHERAPY FOR GLIOBLASTOMA: GENETIC SIGNATURES THAT MAY PREDICT RESPONSIVENESS.

PI: Robert M. Prins, Ph.D.
Assistant Professor of Neurosurgery
University of California Los Angeles (UCLA) School of Medicine

Award: $150,000 for one year

FEASIBILITY STUDY OF A PERSONALIZED AND ADAPTABLE CANCER VACCINE FOR PATIENTS WITH GLIOBLASTOMA.

PI: Duane A. Mitchell, M.D., Ph.D.
Assistant Professor of Neurosurgery
Associate Director, Duke Brain Tumor Immunotherapy Program
The Preston Robert Tisch Brain Tumor Center at Duke

Award: $150,000 for one year

TUMOR-SPECIFIC RADIATION SENSITIZATION IN GLIOBLASTOMA BY TARGETING THE P53-INDEPENDENT CHECKPOINT RESPONSE.

PI: Prakash Chinnaiyan, M.D.
Assistant Member, Department of Radiation Oncology and Experimental Therapeutics
H. Lee Moffitt Cancer Center and Research Institute

Award: $150,000 for one year

CIRCULATING BIOMARKERS THAT PREDICT RESPONSE TO AN IRREVERSIBLE PAN-HER KINASE INHIBITOR IN EGFR-AMPLIFIED GBM.

PI: Andrew S. Chi, M.D., Ph.D.
Divisions of Hematology/Oncology and Neuro-Oncology
Department of Neurology
Massachusetts General Hospital & Harvard Medical School

Award: $150,000 for one year
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