Research Funded To Date

The Ben and Catherine Ivy Foundation is dedicated to finding a cure for brain cancer. We strive in improve the quality of life and increase the life expectancy of those diagnosed with brain cancer by funding promising research that creates more diagnostics and treatments for patients.

Since 2008, we have funded 19 separate institutions with over 65 different research grants totaling over $120 million. These grants have involved research in biomarkers, genomics, imaging, immunotherapy, stem cell, vaccines, and the development of possible new drugs.

2011

A COLLABORATIVE EFFORT BETWEEN TRANSLATIONAL GENOMICS RESEARCH INSTITUTE AND THE IVY EARLY PHASE CLINICAL TRIALS CONSORTIUM (UCSF, UCLA, MSKCC, MGH, DFCC, MD Anderson, Un. of Utah) TO DEVELOP INNOVATIVE CLINICAL TRIALS FOR GBM PATIENTS WHICH WILL MATCH AN INDIVIDUAL’S MOLECULAR PATHOLOGY TO TARGETED THERAPIES, INCLUDING ALIGNING GENOMIC INFORMATION, GLIOMA BIOLOGY, PRECISION GUIDED DELIVERY AND ACCESS TO NEW AGENTS.

PIs: John Carpten, Ph.D.
Deputy Director of Basic Science
Translational Genomics Research Institute (TGen)

David Craig, Ph.D.
Deputy Director of Bioinformatics
Translational Genomics Research Institute (TGen)

Award: $5,000,000 over five years

OUTLIERS IN GLIOBLASTOMA OUTCOME. DEEP GENOMIC ANALYSIS OF SHORT-TERM AND LONG-TERM SURVIVORS OF GBM TO UNDERSTAND THE MOLECULAR BASIS OF RESPONSE TO THERAPY AND TO GUIDE NEW TREATMENT DEVELOPMENT.

PI: Jeffrey M. Trent, Ph.D.
President and Scientific Director
Translational Genomics Research Institute (TGen)

Award: $5,000,000 over five years

DEVELOPMENT OF A NEURO-ONCOLOGY IMAGING PROGRAM USING MRI-PET AND MOLECULAR PROBES FOR IMPROVING THE MANAGEMENT OF GLIOMA.

PI: Sanjiv Sam Gambhir, M.D., Ph.D.
Head of Radiology and Nuclear Medicine Program
Stanford University

Award: $10,000,000 over five years

PERFORM IN DEPTH MOLECULAR CHARACTERIZATION OF CLINICAL SAMPLES TO THE SINGLE CELL LEVEL AND ASSESS THE EFFECTS OF TREATMENT ON CELLULAR AND MOLECULAR HETEROGENEITY BEFORE AND DURING TREATMENT.

PIs: Paul Mischel, M.D.
Professor, Pathology and Laboratory Medicine
University of California Los Angeles (UCLA) School of Medicine

Timothy Cloughesy, M.D.
Director, Neuro-Oncology Program
University of California Los Angeles (UCLA) School of Medicine

James R. Heath, Ph.D.
Elizabeth W. Gilloon Professor
California Institute of Technology

Award: $2,250,000 over three years
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